The reasons for swelling in both ankles are varied and may include conditions such as glomerulonephritis, nephrotic syndrome, right heart failure, and deep vein thrombosis (DVT).
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Glomerulonephritis: This condition results from factors like infection or genetics, leading to impaired glomerular filtration in the kidneys, causing retention of water and sodium in the body, resulting in swelling in the ankles, eyelids, and perineum.
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Nephrotic Syndrome: Characterized by massive proteinuria, hypoalbuminemia, and edema, nephrotic syndrome causes decreased plasma oncotic pressure, increased tissue fluid extravasation, and reduced antidiuretic hormone, leading to water and sodium retention and swelling in various parts of the body, including the ankles and eyelids.
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Right Heart Failure: This occurs when the right ventricle's compensatory function is impaired, causing systemic venous congestion and impaired venous return from the lower limbs, making ankles and feet prone to swelling.
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Deep Vein Thrombosis (DVT): This condition involves abnormal blood clotting in the deep veins, obstructing venous flow and causing venous return obstruction. In such cases, small molecules in the blood can permeate surrounding tissues, resulting in low-protein edema and swelling in both ankles.
Additionally, conditions such as liver cirrhosis, liver dysfunction, renal insufficiency, and medication use may also contribute to swelling in both ankles.
Therefore, it is essential to promptly seek medical attention for comprehensive evaluation and diagnosis, followed by active participation in treatment.
